The three generations of leptons and quarkons have been discovered. The left-right asymmetry in the weak interaction of leptons and quarks has been confirmed. Astronomical observations have showed that the number of baryons and antibaryons is asymmetrical in the observabale cosmos. This paper shows that there is the same origin of the left-right asymmetry and the asymmetry of number of baryons and antibaryons. The three generations of leptons and quarkons and the two sorts of asymmetry are explained in this paper based on the SU(5) grand unified model with hadrons as nontopological solitons.